VP, U.S. Medical Affairs

Responsibilities

• Deliver a highly effective U.S. medical launch to enable evidence-based adoption
• Establish a credible scientific presence with U.S. KOLs, payers, and patient communities
• Build and scale a high-performing Medical Affairs organization, including Field Medical teams
• Define and execute the U.S. Medical Affairs strategy aligned with global objectives
• Oversee U.S. medical tactics including KOL strategy, advisory boards, and medical education
• Provide strategic oversight of U.S.-focused evidence generation and lifecycle management
• Ensure the highest standards of medical integrity, compliance, and ethical conduct
• Serve as the senior U.S. medical spokesperson to external stakeholders

Requirements

• MD, PhD, Pharm D, or other relevant terminal degree
• 20+ years of professional experience, including 10+ years in Medical Affairs
• Rare disease and preferably neuromuscular launch experience
• Experience leading Medical Affairs teams through the commercialization phase
• In-depth knowledge of drug development, market access, and lifecycle management
• Proficiency with Microsoft Suite, MS Project, SharePoint, and Veeva
• Ability to travel up to 50% within the U.S. and internationally
• Fluency in English

Preferred Qualifications

• Experience working with diverse cultural backgrounds and learning styles
• Demonstrated executive presence and ability to influence at all organizational levels
• Experience in a matrix environment

About the Company

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease.