Vice President, Translational Medicine & Clinical Biomarkers

About the Company

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases.

Responsibilities

• Define and own the enterprise-wide translational medicine and clinical biomarker strategy across the pipeline
• Design and implement predictive biomarker strategies and translational plans to support indication selection
• Oversee the full lifecycle of biomarker program development from preclinical discovery through clinical validation
• Integrate advanced translational data modalities including ctDNA/ctRNA, single-cell sequencing, and spatial transcriptomics
• Provide scientific leadership for translational and biomarker content in clinical protocols and regulatory submissions
• Lead clinical biomarker data interpretation and synthesis across programs
• Build, inspire, and develop a high-performing team of translational scientists and biomarker specialists
• Manage the translational medicine operating model, including CRO and diagnostic partner strategy

Requirements

• Ph.D. in Immunology, Oncology, Biochemistry, Cell Biology, or a related life sciences discipline
• 15+ years of progressive experience in translational medicine or clinical biomarker research in biopharma
• 10+ years in a senior leadership role (Sr. Director level or above) with direct management of scientific staff
• Demonstrated track record of leading translational programs from IND through Phase I/II
• Experience with regulatory submissions and health authority interactions (FDA, EMA)
• Deep expertise in target engagement, pharmacodynamic, predictive, and safety biomarkers
• Hands-on knowledge of technologies such as flow cytometry, ELISA/MSD, IHC/mIF, and NGS

Preferred Qualifications

• MD/Ph.D. degree
• Direct experience with targeted protein degradation (PROTACs, molecular glues)
• Experience in both oncology and immunology/inflammatory disease therapeutic areas
• Experience building a translational medicine function from an early stage
• Familiarity with AI-driven approaches in translational science and multi-omic integration