Technician B

Responsibilities

• Maintain and experimentally manage specialized zebrafish lines, including handling, breeding, crossing, embryo collection, and colony management
• Perform and optimize experimental workflows to support functional studies of Alzheimer’s disease risk variants
• Assist in the development of in vivo screening paradigms
• Maintain rigorous experimental documentation to ensure reproducible, high-quality science
• Support core laboratory infrastructure and collaborate with trainees and senior scientists

Requirements

• Bachelor’s degree in neuroscience, biology, genetics, chemistry, or a closely related discipline (or equivalent in education and experience)

Preferred Qualifications

• Demonstrated familiarity with zebrafish handling and experimental workflows (crossing, embryo collection)
• Direct, hands-on experience with CRISPR/Cas9 gene editing (design, synthesis, injection, and/or screening)
• Experience with microscopy or tissue-based experimental techniques
• Experience contributing to experimental or phenotypic screening approaches
• Prior exposure to neurobiology, functional genomics, or genetic disease modeling
• Strong organizational skills and the ability to work independently within a collaborative team

About the Company

The Kizil Laboratory at Columbia University Irving Medical Center (CUIMC) focuses on the functional interpretation of human genetic variation in Alzheimer’s disease using advanced zebrafish models. CUIMC is a leading academic medical center at the forefront of biomedical research, clinical innovation, and scientific training in New York City.