Staff Site Reliability Engineer (SRE)

Responsibilities

• Design, build, and operate highly available, fault-tolerant cloud infrastructure across AWS, GCP, and/or Azure
• Architect and maintain scalable CI/CD pipelines and deployment frameworks for enterprise-grade software delivery
• Lead infrastructure-as-code adoption and maturity using tools such as Terraform, CloudFormation, and Ansible
• Own Kubernetes reliability across multi-cluster environments, including upgrades, scaling, and workload lifecycle management
• Establish and evolve observability platforms and define SLO/SLI frameworks across teams
• Lead incident response for critical outages, drive root cause analysis, and implement preventative improvements
• Optimize infrastructure for cost, performance, and scalability
• Mentor engineers and contribute to technical leadership through design reviews and standards

Requirements

• BS in Computer Science, Engineering, or a related field, or equivalent experience
• 8+ years of experience in Site Reliability Engineering, DevOps, or platform engineering
• Strong hands-on experience with at least one major cloud platform (AWS, GCP, or Azure)
• Experience implementing infrastructure-as-code solutions (Terraform, CloudFormation, or similar)
• Experience designing and operating CI/CD pipelines (e.g., GitLab CI, GitHub Actions, Jenkins)
• Hands-on experience with Kubernetes and containerized systems in production environments
• Proficiency in scripting or programming for automation (e.g., Python, Go, Bash)
• Experience with observability and monitoring tools (e.g., Prometheus, Grafana, Datadog)
• Experience working in regulated environments (e.g., HIPAA, SOC 2, ISO 27001, or NIST)

Preferred Qualifications

• 10+ years of experience in SRE, DevOps, or infrastructure engineering
• Experience operating multi-cluster Kubernetes environments (e.g., EKS, GKE) at scale
• Familiarity with GitOps practices (e.g., ArgoCD, Flux)
• Experience with data platforms and pipelines (e.g., Kafka, Airflow, Spark, Snowflake)
• Strong background in cloud security, including IAM and zero-trust architecture
• Experience with compliance-as-code and security tooling (e.g., OPA, Snyk, Checkov)
• Exposure to AI/ML or large-scale data infrastructure workloads

About the Company

GRAIL is a healthcare company pioneering new technologies to advance early cancer detection. We use next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science to transform cancer care and change the trajectory of cancer mortality.