Staff Bioinformatics/Machine Learning Scientist

Responsibilities

• Lead the development, evaluation, and optimization of machine learning and statistical models for high-dimensional NGS and genomics datasets
• Design and implement bioinformatics algorithms to support assay development, quality control, and signal detection
• Collaborate with wet-lab scientists to design experiments and interpret complex biological results
• Apply rigorous statistical methods to evaluate assay performance, reproducibility, and robustness
• Develop reproducible analysis workflows using modern bioinformatics and software engineering practices
• Work within cloud computing environments to manage and analyze large-scale sequencing datasets
• Provide technical leadership, mentorship to junior team members, and subject matter expertise in NGS bioinformatics

Requirements

• Ph.D. in bioinformatics, computational biology, computer science, mathematics, or a related field
• 8+ years of experience in bioinformatics within industry or academia
• 6+ years of experience in the biotech, life science, or pharmaceutical industry
• Demonstrated expertise in developing statistical and quantitative methods
• Deep understanding of molecular biology, biochemistry, and next-generation sequencing (NGS)
• Proven experience in product or assay research, design, or development

Preferred Qualifications

• 10+ years of experience in the biotech or life science industry
• Practical experience leveraging AI in regulated environments
• Experience with modern cloud-based MLOps systems
• Expertise in applying deep learning and advanced statistical learning to complex datasets
• Previous experience as a project lead or in direct people management
• Experience working in a molecular diagnostics or GMP/ISO regulated environment

Benefits

• Paid time off including vacation, holidays, and volunteering
• Paid leave for parents and caregivers
• Retirement savings plan
• Comprehensive health benefits including medical, prescription drug, dental, and vision coverage
• Wellness support

About the Company

Exact Sciences is dedicated to helping change how the world prevents, detects, and guides treatment for cancer. We provide patients and clinicians with the clarity needed to make confident decisions through innovative molecular diagnostics.