Sr. Director, Program Management & Business Operations

Responsibilities

• Lead program teams for the company's lead program and future pipeline assets, driving scientific rigor and accountability from research through clinical stages.
• Define program strategies, objectives, and cross-functional plans, including timelines, budgets, and resource allocation.
• Identify and mitigate program risks, bottlenecks, and issues proactively.
• Serve as Chief of Staff to the Leadership Team, driving collaboration, alignment, and execution on key organizational priorities.
• Develop strategic plans, long-range planning assumptions, and portfolio-level analyses to support business processes.
• Prepare executive-level communications, presentations, and strategic materials for the Board of Directors and Leadership Team.
• Support the CEO and Leadership Team in partnership discussions, negotiations, and due diligence activities.
• Map the competitive landscape to identify emerging threats and opportunities.

Requirements

• BS/MS degree in a scientific discipline (ideally life science or chemistry).
• 15+ years of relevant experience in pharma or biotech drug discovery and development.
• 10+ years of Program Management experience, preferably in early-stage drug discovery and development.
• Proven experience leading cross-functional teams through the drug development lifecycle.
• Comprehensive understanding of both preclinical and clinical drug discovery processes.

Preferred Qualifications

• Experience in the development of advanced therapies to treat rare genetic diseases.
• Experience serving in a Chief of Staff or high-level operational leadership capacity.

Benefits

• Competitive salary range ($213,000 - $280,500).
• Healthcare coverage.
• Annual incentive program.
• Retirement benefits.

About the Company

Alltrna is a clinical-stage biotech company advancing tRNA medicines to address shared disease-causing mutations. Founded by Flagship Pioneering, Alltrna utilizes an integrated platform to design, optimize, and deliver engineered tRNA therapeutics to treat diseases caused by premature termination codons.