Senior Statistical Geneticist

Responsibilities

• Design, execute, and interpret analyses of diverse quantitative and binary traits in large-scale population cohorts to support internal research and external opportunity evaluation.
• Perform integrative analyses of human genetics and EHR data to enable target identification, biomarker discovery, and clinical development decisions.
• Collaborate with cross-functional stakeholders, including biology, clinical, and business development teams, to translate findings into actionable insights.
• Communicate results through internal presentations, written reports, and contributions to scientific publications and conferences.
• Contribute to building and maintaining computational tools and infrastructure for streamlined, reproducible analyses.

Requirements

• PhD in Statistical Genetics, Human Genetics, Computational Biology, or a related discipline.
• 5+ years of industry experience.
• Demonstrated hands-on experience working with UK Biobank and All of Us data, including understanding of their data architecture.
• Extensive experience with QC, analysis, and interpretation of human genetics data (single-variant and gene-based association analyses using WES/WGS/array genotyping data).
• Proficiency in Python and experience integrating AI-powered tools into analytical workflows.

Preferred Qualifications

• Experience inferring disease incidence and prevalence from genetics data.
• Familiarity with large-scale human genomics databases such as gnomAD, GTEx, 1000 Genomes, or TOPMed.
• Experience supporting target validation or biomarker discovery in a pharmaceutical or biotechnology setting.
• Familiarity with multi-omics data types, including transcriptomics, proteomics, epigenomics, or chromatin accessibility.

Benefits

• Market-leading compensation, including base pay, annual performance bonus, and company equity.
• 100% employer-paid medical, dental, and vision premiums for employees and dependents.
• 401(k) with employer match and Employee Stock Purchase Program (ESPP).
• Flexible, “take-what-you-need” paid time off and comprehensive paid medical and parental leave.
• Fertility and family-forming benefits, plus expanded mental health support.

About the Company

BridgeBio is a biopharmaceutical company that uses a unique "moneyball for biotech" approach to accelerate the development of life-changing medicines for patients with unmet needs in rare diseases. We value curiosity, experimentation, and the ethical use of AI to push the boundaries of science.