Senior Scientist, Inflammation Biomarkers & Translational Research

Responsibilities

• Lead end-to-end biomarker strategies for clinical programs from early translational research through Phase I-III studies.
• Define and implement pharmacodynamic, MOA, prognostic, and predictive biomarkers, including assay qualification and validation.
• Serve as the biomarker lead for cross-functional program teams, providing scientific direction and risk assessment.
• Oversee biomarker operations, including CRO management, vendor oversight, and data quality assurance.
• Design and oversee human-relevant translational studies using primary human samples.
• Integrate multi-omic, spatial, and clinical datasets to generate actionable insights for program decisions.
• Author and review clinical biomarker sections for protocols, Investigator Brochures (IBs), and regulatory documents.
• Represent the organization in health authority interactions (FDA, EMA) and present data at scientific conferences.

Requirements

• PhD in Immunology, Inflammation Biology, Translational Medicine, or a related discipline.
• 5–8+ years of relevant post-doctoral and industry experience.
• Deep understanding of human immunology, inflammation, and/or fibrotic disease biology.
• Proven experience designing and implementing clinical biomarker strategies, including assay validation and outsourcing.
• Strong record of scientific contributions, such as high-profile publications or patents.
• Excellent communication skills with the ability to influence cross-functional stakeholders.

Preferred Qualifications

• Demonstrated ability to lead biomarker strategy for Phase I–III clinical trials in regulated environments.
• Prior experience interacting with health authorities on biomarker-related topics.
• Familiarity with high-dimensional platforms such as flow/mass cytometry, single-cell, or spatial biology.
• Working knowledge of data analysis tools like R or Python for biomarker interpretation.

About the Company

Gilead Sciences is a research-based biopharmaceutical company that has tackled diseases such as HIV, viral hepatitis, COVID-19, and cancer for more than 35 years. We work relentlessly to develop therapies that improve lives and ensure global access to life-changing scientific innovations.