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Posted 3 days ago
Senior Scientist, Conjugation Biochemistry
Flagship Labs 103, Inc.Senior Scientist, Conjugation Biochemistry
Requirements
Ph.D. in Biochemistry, Chemistry, or related discipline, 5+ years bioconjugation industrial experience, Expertise in oligonucleotide conjugates, Proficiency in RP-HPLC, FPLC, SEC, and IEX, Experience with antibody and protein conjugation
Skills
Biochemistry
About the role
Responsibilities
- Design, synthesize, purify, and analyze oligonucleotide-conjugates on antibodies and other modalities
- Develop and optimize conjugation protocols using established and novel chemistries and technologies
- Collaborate with the assay development team to guide and optimize conjugates for research programs
- Work within cross-functional teams to manage project timelines and communicate progress
- Establish working relationships with collaborative partners to advance discovery research to pre-clinical development
- Prepare research reports and presentations for internal leadership and external audiences
- Maintain organized lab notebooks and batch records
Requirements
- Ph.D. in Biochemistry, Chemistry, or a related scientific discipline
- 5+ years of bioconjugation-related industrial experience, specifically in designing and validating oligonucleotide conjugates
- Hands-on expertise with bioconjugation techniques for antibodies, proteins, peptides, and other biomolecules
- Proficiency in analytical characterization and purification techniques including RP-HPLC, FPLC, SEC, and IEX
- Strong problem-solving skills and a proactive approach to exploring new scientific methodologies
- Excellent written and verbal communication skills for presenting complex data to senior leadership
About the Company
Flagship Labs 103, Inc. is a privately held early-stage company building advanced technological and computational platforms to pioneer the detection of cellular dynamics from minimally invasive biospecimens. Our mission is to connect individuals to effective interventions to prevent the onset and progression of disease. We are part of the Flagship Pioneering ecosystem, a bioplatform innovation company that has originated more than 100 scientific ventures.
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Flagship Labs 103, Inc. · Cambridge
