Senior Scientist, Biologics Formulation

Responsibilities

• Lead formulation development programs for high concentration protein therapeutics across various dosage forms
• Design and execute formulation strategies based on first-principles understanding of protein chemistry, solution behavior, and colloidal stability
• Identify and mitigate formulation-related risks such as aggregation, precipitation, viscosity, and chemical degradation
• Serve as the technical lead on multiple concurrent formulation projects from early-stage through late-stage development
• Establish formulation development workflows, analytical strategies, and acceptance criteria
• Mentor junior scientists and provide technical guidance to the team
• Maintain high standards for data management, ELN documentation, and scientific rigor

Requirements

• PhD in Pharmaceutical Sciences, Biomaterials, Materials Science, Chemistry, Chemical Engineering, Biochemistry, or a related discipline
• 3+ years of biopharmaceutical industry experience in protein formulation development
• Deep expertise in protein chemistry, physical biochemistry, and formulation science
• Extensive hands-on experience with analytical techniques including DLS, DSF, SEC, CE, rheology, or spectroscopy
• Proven experience developing high-concentration protein formulations and mitigating concentration-limiting factors
• Ability to work independently in a fast-paced startup environment
• Must be a "U.S. Person" as defined by ITAR regulations

Preferred Qualifications

• Experience with protein crystallization for drug delivery
• Knowledge of advanced formulation systems and lyophilization or spray drying processes
• Familiarity with Design of Experiments (DOE) and statistical analysis
• Experience with high-throughput formulation screening and automation
• Background in monoclonal antibodies, antibody-drug conjugates, or other complex biologics

Benefits

• Equity in a fully funded space startup
• 401(k) matching
• Unlimited PTO
• Health insurance, including Vision and Dental
• On-site lunch and snacks, with dinners provided twice a week

About the Company

Varda is accelerating the development of commercial space infrastructure, from in-orbit pharmaceutical processing to reliable and economical reentry capsules. Our mission is to expand the economic bounds of humankind by creating the products and infrastructure needed so space can directly benefit life on Earth.