Senior Scientist, Bioanalytical Science

About the Company

Seaport Therapeutics is a clinical-stage therapeutics company advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs. The Company utilizes its proprietary Glyph™ technology platform to enable oral bioavailability and reduce side effects.

Responsibilities

• Support the development and optimization of bioanalytical methods (e.g. LC/MS) to evaluate concentration of API, metabolites, and related species
• Manage execution of method development and sample analysis across multiple external CROs and collaborators
• Assist in design and selection of methods of sample extraction and analysis across matrices including lymph, plasma, and solid tissues
• Perform pharmacokinetic analysis of data and provide scientific interpretations to cross-functional teams
• Contribute to the development or application of relevant pharmacokinetic models
• Coordinate bioanalytical laboratory operations including equipment maintenance and inventory management
• Actively participate in team meetings and contribute to reports and patent applications

Requirements

• MS/PhD in analytical chemistry, bioanalytical chemistry, or pharmaceutical analysis
• 3+ years of experience for PhD or 8+ years for MS
• Track record of supporting development and validation of bioanalytical LC-MS/MS methods
• Hands-on familiarity running and maintaining mass spectrometry instrumentation
• Experience with CROs and managing outsourced studies
• Understanding of FDA/global regulatory requirements and GLP
• Excellent cross-disciplinary communication skills