Senior Scientist - Analytical Chemistry, Purification

About the Company

Satomic’s mission is to close the gap from idea to molecule with faster navigation of chemical space. We are building an automated chemistry platform that integrates laboratory robotics, software, and AI to transform small-molecule synthesis and drug discovery.

Responsibilities

• Day-to-day operation of the SFC and reverse-phase LC purification fleet
• Method development, run execution, fraction collection strategy, and data review
• Develop and maintain generic, automation-friendly purification methods
• Perform preventive maintenance, diagnostics, and troubleshooting across SFC, LC, and LC/MS systems
• Partner with synthetic chemistry to understand sample characteristics
• Collaborate with software and automation teams to integrate purification workflows
• Manage solvent, waste, and consumables for the purification fleet
• Develop training materials and protocols for new lab staff

Requirements

• Ph.D. in Analytical Chemistry, Chemistry, or related field with 4+ years of industry experience (or M.S. with 6+ years, or B.S. with 10+ years)
• Extensive hands-on experience with chromatography-based purification of organic small molecules
• Core expertise in SFC and strong experience in high throughput preparative LC/SFC
• Strong experience operating and troubleshooting LC, LC/MS, and SFC/MS hardware
• Ability to develop generic purification methods for diverse small-molecule sets
• Familiarity with purification informatics and automation tools (e.g., Analytical Studio, MassLynx, KNIME)

Preferred Qualifications

• Mass-directed purification experience
• Experience with Waters analytical/preparative SFC instrumentation and software
• Experience with Agilent LC/MS systems