Senior Scientist

Responsibilities

• Serve as a subject matter expert in nonclinical safety pharmacology on cross-functional project teams.
• Develop and execute integrated safety pharmacology strategies supporting discovery, candidate selection, and regulatory submissions.
• Design and oversee GLP and non-GLP safety pharmacology studies conducted internally or at external CROs.
• Evaluate and integrate nonclinical data (cardiovascular, respiratory, CNS, ECG, etc.) to assess biological relevance and translational significance.
• Author safety pharmacology sections for regulatory documents, including IND-enabling summaries, Investigator’s Brochures, and briefing documents.
• Contribute to the development of innovative safety pharmacology approaches and risk-based assessment frameworks.
• Represent Amgen externally through scientific presentations, publications, and participation in industry working groups.

Requirements

• Doctorate degree with 1 year of scientific experience, OR
• Master’s degree with 3 years of scientific experience, OR
• Bachelor’s degree with 5 years of scientific experience.
• Expertise in nonclinical safety pharmacology.
• Experience with regulatory document authoring.

Preferred Qualifications

• PhD in Pharmacology, Neuroscience, Physiology, Biomedical Sciences, or a related field.
• Broad experience in nonclinical safety pharmacology across cardiovascular, respiratory, and CNS domains.
• Experience serving as a study director or subject matter expert for GLP/non-GLP studies.
• Proven ability to collaborate across disciplines and influence in a matrixed environment.
• Track record of scientific publications and participation in professional societies.

Benefits

• Comprehensive health and welfare plans, including medical, dental, and vision coverage.
• Retirement and Savings Plan with company contributions.
• Discretionary annual bonus program and stock-based long-term incentives.
• Award-winning time-off plans and flexible work models where possible.

About the Company

Amgen is a leading biotechnology company dedicated to serving patients living with serious illnesses. Since 1980, we have pioneered advancements in oncology, inflammation, general medicine, and rare diseases. Our mission is to unlock the potential of biology to deliver innovative human therapeutics that improve health outcomes and transform lives.