Senior Scientific Software Engineer, Analytics and Workflows

Responsibilities

• Establish and maintain workflows, libraries, and stand-alone tools for transcriptomics and epigenetic data analysis at both bulk and single-cell levels.
• Evaluate, refine, and productionize analytical workflows to support drug pipeline decisions.
• Collaborate with computational scientists to translate analytical needs into reusable software components.
• Partner with interdisciplinary teams of Software Engineers, Computational Biologists, and Data Scientists to develop scientific tools and interfaces.
• Manage FAIR data principles, including tracking data lineage and ensuring data quality and discovery.

Requirements

• PhD in Software Engineering, Computer Science, Bioinformatics, or a related field with 2 years of relevant experience, OR a Master's degree with 5 years of relevant experience.
• Expert knowledge of R package development and familiarity with the Posit toolchain.
• Proven experience analyzing large-scale single-cell and bulk datasets using R.
• Proficiency in integrating and analyzing multimodal biological data using scalable formats such as Parquet, tileDB, Zarr, or H5.
• Experience working with REST APIs, MCPs, and modern programmatic data science interfaces.
• Demonstrated ability to manage the full software development lifecycle following modern practices.

Preferred Qualifications

• Experience with the Bioconductor and Tidyverse ecosystems.
• Proficiency in RMarkdown, Quarto, Shiny, or Plumber deployment.
• Experience with Python technologies including Pandas, Polars, Streamlit, or FastAPI.
• Prior experience working within a life sciences or drug development environment.

Benefits

• Highly collaborative and dynamic research environment.
• Access to large-scale datasets, advanced compute resources, and state-of-the-art technologies.
• Participation in professional seminar series featuring academic and industry leaders.
• Campus-like lifestyle with a focus on healthy work-life balance.
• Mentored opportunities for professional skill development.

About the Company

Genentech, a member of the Roche group, is a pioneer in the biotechnology industry. We are dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Through our Computational Sciences Center of Excellence, we harness the power of AI and data to accelerate drug discovery and transform patient care worldwide.