Senior Research Associate/Scientist, Drug Product Process Development and Manufacturing

Responsibilities

• Perform hands-on formulation and drug product process development for mRNA-LNP therapeutics, AAV gene therapy, and protein drug products
• Design and execute experiments for excipient selection, concentration optimization, and compatibility studies
• Develop and scale up manufacturing processes by optimizing critical process parameters (CPPs) and critical quality attributes (CQAs)
• Conduct stability testing to assess long-term integrity and identify degradation pathways
• Collaborate with CDMOs to optimize manufacturing processes and provide technical support for GMP activities
• Maintain accurate laboratory records and contribute to development reports and regulatory submissions

Requirements

• Ph.D. in chemical engineering, biochemical engineering, biotechnology, pharmaceutical sciences, or related field with 2–3 years of industry experience (for Scientist level)
• Master’s degree in a related discipline with minimum 6 years of industry experience in drug product process development (for Senior Research Associate level)
• Hands-on experience with mRNA-LNP formulation and/or process development
• Experience with formulation development, process optimization, and drug product development
• Experience with drug product unit operations such as filling, filtration, and mixing
• Understanding of physical and chemical stability of biologics
• Ability to work onsite five days per week in Redwood City, CA

Preferred Qualifications

• Experience with protein therapeutics or AAV gene therapy formulation development
• Experience with scale-down model development, characterization, and scale-up

About the Company

Altos Labs is a biotechnology company dedicated to restoring cell health and resilience through cell rejuvenation to reverse disease, injury, and disabilities.