Senior Research Associate, In Vivo Pharmacology

Responsibilities

• Independently develop and perform in vivo studies using animal models across oncology, autoimmunity, and metabolism disease areas
• Support screening, characterization, and mechanism of action studies for various drug modalities, including small molecules, biologics, and nucleic acids
• Generate high-quality data and monitor animal health in compliance with IACUC regulations
• Develop ex vivo assays in collaboration with translational science to determine pharmacodynamic biomarkers
• Collaborate with in vitro biology and translational teams to support daily operations in the vivarium and laboratory
• Accurately record experimental results and documentation via Electronic Lab Notebook (ELN)

Requirements

• BSc or advanced degree in Biology or a related discipline
• 2+ years of experience in animal handling within a research setting
• Expertise in multiple forms of substance administration (e.g., PO, IP, IV, SC)
• Experience in necropsy, tissue collection, and processing
• Proficiency in scientific software including Excel, GraphPad Prism, and FlowJo
• Demonstrated ability to execute in vitro and ex vivo assays such as cell culture, ELISA, or Flow cytometry
• Strong ability to analyze scientific data and communicate findings to internal stakeholders

Preferred Qualifications

• Research background in oncology, immunology, or metabolism in an industry or academic setting
• Previous experience specifically with animal models of metabolism, oncology, and autoimmunity
• Hands-on experience with flow cytometry

Benefits

• Healthcare coverage
• Annual incentive program
• Retirement benefits
• A broad range of other company benefits

About the Company

Pioneering Medicines, a division of Flagship Pioneering, is building a world-class biopharmaceutical R&D capability. We focus on conceiving and developing life-changing treatments by harnessing the power of Flagship's scientific platforms to address serious diseases with unmet medical needs.