Senior Manager, Program Management and Drug Substance Lead

Responsibilities

• Drive day-to-day program execution across drug substance activities and maintain integrated timelines
• Support drug substance activities for biologics, including CHO cell line–based processes
• Coordinate activities across CDMOs and external partners to track manufacturing progress
• Partner with Supply Chain to align drug substance manufacturing with clinical and commercial demand
• Identify program and technical risks and support development of mitigation plans
• Coordinate across Quality, Regulatory, Clinical, Commercial, and Finance teams
• Maintain program plans, trackers, and dashboards using tools such as Smartsheet

Requirements

• Bachelor’s degree in life sciences, engineering, or related field
• 6–10+ years of experience in biologics drug substance development, manufacturing, or CMC program management
• Required experience with CHO cell-based manufacturing systems
• Working knowledge of upstream (cell culture) and downstream (purification) processes
• Experience supporting tech transfer, scale-up, and manufacturing execution
• Experience working with external manufacturing partners (CDMOs)
• Strong program management and data management skills

Preferred Qualifications

• Advanced degree in a related field
• Experience with Smartsheet

About the Company

Vor is advancing telitacicept, a first-in-class dual BAFF/APRIL inhibitor, to address autoimmune diseases at their root cause.