Senior Director, Portfolio Reporting & Analytics

Responsibilities

• Design and advance a next-generation clinical and portfolio insights platform for real-time reporting and analytics
• Establish a single source of truth by integrating internal and external operational data from CROs and vendors
• Architect a centralized operational data infrastructure in partnership with IT/Digital
• Develop standard analytical frameworks, KPIs, and visualization standards for clinical studies and portfolios
• Lead the creation of advanced analytics and simulation capabilities to predict development timelines, costs, and risks
• Deploy AI/ML-powered prescriptive analytics to provide actionable recommendations and scenario modeling
• Develop predictive country and site selection analytics to optimize trial delivery
• Design an integrated resource management capability to analyze demand vs. actuals and predict capacity bottlenecks
• Drive change management and adoption of new analytics capabilities across the organization

Requirements

• Bachelor’s degree in a quantitative or life sciences field (e.g., Statistics, Data Science, Engineering, Biology)
• 15+ years of experience in biopharma/biotech R&D with a focus on clinical operations analytics or portfolio management
• 5+ years of experience leading multi-disciplinary teams
• Proven track record building enterprise data and analytics platforms for R&D portfolios
• Expertise in portfolio, program, and study KPIs and scenario modeling
• Hands-on experience with advanced analytics, ML, forecasting, and simulation
• Strong understanding of the clinical development lifecycle and GCP/GxP expectations
• Exceptional executive presence and ability to influence senior stakeholders

Preferred Qualifications

• Master’s or PhD in Data Science, Biostatistics, or Operations Research
• MBA degree
• Experience with site/country selection analytics and enrollment prediction
• Familiarity with R&D systems such as CTMS, EDC, eTMF, and RTSM
• Background in data governance and data product management

About the Company

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for FSHD and Pompe disease.