Senior Director, Delivery

About the Company

Sail Biomedicines is pioneering the integrative design and deployment of fully programmable medicines to transform patient care. Sail’s platform combines first-in-class programmable circular RNA technology and an industry-leading platform of programmable nanoparticles to unlock comprehensive programming of medicines.

Responsibilities

• Lead and grow Sail’s Delivery team, advancing lipid nanoparticle (LNP) and targeted delivery technologies.
• Drive innovation in targeted nanoparticles, including design, formulation, ligand selection, and conjugation.
• Define and execute delivery strategy across tissues and disease areas to guide nanoparticle engineering.
• Develop and apply high-throughput screening approaches to evaluate delivery performance.
• Partner with Program and Technical Development teams to ensure scalable, robust processes supporting progression to clinic.
• Manage external collaborations, including CROs and technology partners.
• Advise senior leadership on delivery strategy, portfolio prioritization, and execution risks.

Requirements

• PhD or MD in drug delivery, chemical engineering, materials science, pharmaceutical sciences, or a related discipline
• 12+ years of relevant industry experience
• Deep expertise in lipid nanoparticle (LNP) systems, including formulation and lipid chemistry
• Demonstrated experience in targeted delivery approaches such as ligand conjugation and receptor-mediated targeting
• Strong understanding of nucleic acid delivery challenges including biodistribution and endosomal escape
• Experience advancing delivery technologies toward IND-enabling studies or clinical translation
• Proven track record of leading multidisciplinary scientific teams in a biotech environment