Senior Director, Clinical Development

Responsibilities

• Serve as the medical lead for clinical programs, providing strategic and operational leadership across study design, execution, analysis, and reporting.
• Lead cross-functional clinical study teams and provide medical oversight to ensure participant safety, data quality, and protocol compliance.
• Partner with investigators, key opinion leaders, advocacy organizations, and CRO partners to execute high-quality clinical trials.
• Author and review protocols, investigator brochures, clinical study reports, DSURs, and regulatory submission content.
• Lead medical monitoring activities and contribute to safety review meetings and regulatory authority interactions.
• Translate clinical, translational, and nonclinical findings into actionable development strategies and lifecycle plans.

Requirements

• MD or equivalent medical degree is required.
• 5+ years of biotechnology, pharmaceutical, or clinical development experience with increasing medical leadership responsibilities.
• Demonstrated expertise in clinical trial design, medical monitoring, protocol development, and data interpretation.
• Strong understanding of ICH-GCP, FDA, EMA, and global regulatory requirements.
• Exceptional communication, collaboration, and stakeholder management skills.

Preferred Qualifications

• Board certification in Endocrinology, Nephrology, or a related specialty.
• Experience in rare disease, endocrinology, metabolic disease, or chronic hypoparathyroidism drug development.

Benefits

• Market-leading compensation and company equity.
• 100% employer-paid medical, dental, and vision premiums for employees and dependents.
• 401(k) with employer match and Employee Stock Purchase Program (ESPP).
• Flexible, “take-what-you-need” paid time off and comprehensive parental leave.
• Hybrid work model with subsidized lunch and parking on in-office days.

About the Company

BridgeBio Pharma is a mission-driven biotechnology company that uses a unique "moneyball for biotech" approach to develop life-changing medicines for patients with unmet needs in rare diseases. We value curiosity, experimentation, and the empowerment of experts to solve complex scientific problems.