Senior Bioinformatics Analyst

Responsibilities

• Design, build, and deploy end-to-end machine learning pipelines from raw data ingestion through production deployment.
• Develop predictive models for DNA-Encoded Library (DEL) screening data and other high-dimensional biomedical datasets.
• Implement and fine-tune deep learning architectures, including transformers, graph neural networks, and generative models.
• Perform rigorous exploratory data analysis, statistical modeling, and visualization to identify patterns in large biomedical datasets.
• Establish and maintain MLOps best practices, including model versioning, pipeline automation, and experiment tracking.
• Collaborate with structural biologists, medicinal chemists, and bioinformaticians to translate scientific questions into ML solutions.
• Present technical findings and model performance to both technical collaborators and non-technical stakeholders.

Requirements

• Degree in Computer Science, Data Science, Bioinformatics, Computational Chemistry, or a related field.
• Master’s degree with 4 years of related experience, or a Bachelor’s degree with 6 years of related experience.
• Proven experience designing and implementing machine learning models in drug discovery or biomedical domains.
• Strong expertise in Python and libraries such as scikit-learn, pandas, and NumPy.
• Proficiency in deep learning frameworks like TensorFlow, PyTorch, or Keras.
• Experience with MLOps practices and tools (e.g., MLflow, Airflow).
• Hands-on experience with high-dimensional biomedical datasets or DEL data.

Preferred Qualifications

• Experience building transformers, graph neural networks, or generative models for molecular property prediction.
• Demonstrated ability to innovate on new model architectures for drug discovery.

Benefits

• Competitive compensation packages.
• Membership in the Healthcare of Ontario Pension Plan (HOOPP).
• Flexible work environment.
• Opportunities for professional development and promotion within a large organization.
• Access to transit and UHN shuttle services.
• Various corporate discounts including travel, restaurants, and parking.

About the Company

University Health Network (UHN) is Canada’s #1 hospital and a global leader in publicly funded healthcare and research. As a top research hospital affiliated with the University of Toronto, UHN conducts major research in neurosciences, oncology, genomic medicine, and more. Join the Structural Genomics Consortium at UHN to help accelerate drug discovery through cutting-edge AI and machine learning.