Scientist/Senior Scientist, Immunology

About the Company

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells.

Responsibilities

• Collaborate with Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design and evaluate epigenetic reprogramming interventions
• Develop scalable functional assays in T cells and Tregs to predict therapeutic activity
• Design and lead in vivo and in vitro immunology studies to support target discovery and preclinical development
• Drive research in Treg biology, including differentiation, stability, and suppressive function
• Author or contribute to study reports, internal data packages, and regulatory-supporting documentation
• Mentor junior scientists and foster a collaborative, rigorous scientific culture

Requirements

• Ph.D. in immunology, cell biology, or a related field with 2+ years of industry experience, or BS/MS with 8+ years of relevant industry experience
• Hands-on experience with multi-parameter flow cytometry
• Experience designing in vivo models of autoimmune or inflammatory disease
• Experience with primary immune cell isolation, ex vivo culture, and Treg functional assay
• Experience authoring IND-supporting study reports

Preferred Qualifications

• Experience with pooled in vitro or in vivo screening approaches (e.g., CRISPR fitness screens, Perturb-seq, CROP-seq)
• Experience with rheumatoid arthritis and/or colitis models
• Experience managing or partnering with CROs to support preclinical studies
• Familiarity with basic computational tools for data analysis (e.g., Python, R)

Benefits

• Health, dental, and vision insurance
• 401(k) with company match
• Paid parental leave
• 20 days of PTO per year plus holidays
• On-site meals and snacks