Scientist, RNA Biochemistry

About the Company

Cloverleaf Bio is an early-stage therapeutics company that is developing a new class of engineered tRNA therapeutics. Our tRNAs target an underappreciated vulnerability of cancer: addiction to high levels of tRNA modifying enzymes.

Responsibilities

• Design and perform low and high-throughput RNA screening assays
• Generate RNA sequencing libraries
• Perform mechanistic studies in cells on lead candidate RNAs
• Explore new disease areas beyond oncology

Requirements

• PhD in Biochemistry, Molecular Biology, Genetics or related fields
• Strong problem solving skills
• Ability to independently drive research projects to completion
• Experience with RNA/DNA extraction, PCR, RT-PCR, qPCR, and western blotting
• Proficiency in mammalian cell culture and passaging

Preferred Qualifications

• Competency generating libraries for RNA sequencing (mRNA-seq, CLIP-seq, etc.)
• Ability to analyze NGS data using bioinformatics tools
• Research experience in tRNA, RNA biology, or RNA modifications
• Experience with RNA therapeutics design and lipid nanoparticles
• Experience with mouse models of oncology

Benefits

• Competitive salary and strong equity incentives
• Medical, dental, and vision coverage
• Brand new lab space in BioLabs New Haven