Posted 3 days ago
Scientist, LNP Process and Development
Serif BiomedicinesScientist, LNP Process and Development
Requirements
PhD in Chemical Engineering, Pharmaceutical Sciences, or Bioengineering with 3+ years industry experience, MS with 8+ years experience, Bachelors with 10+ years experience, Background in process development or scale-up of nanoparticle systems, Experience with nucleic acid formulations (mRNA, DNA), Familiarity with T mixing and characterization techniques like DLS
Skills
Process Development
About the role
Responsibilities
- Support process development and optimization activities for LNP formulation and scale-up, including mixing parameters, encapsulation efficiency, and reproducibility
- Design and execute experiments to improve the performance and manufacturability of LNPs encapsulating modified DNA and mRNA
- Collaborate with internal and external teams to support characterization and evaluation of LNP formulations
- Assist with technology transfer and scale-up activities, including coordination with external partners or internal manufacturing teams
- Analyze and interpret experimental data, maintain accurate documentation, and communicate findings to project teams
- Stay current with advancements in LNP technologies and nucleic acid delivery approaches
Requirements
- PhD in Chemical Engineering, Pharmaceutical Sciences, Bioengineering, or a related field with 3+ years of industry experience; MS with 8+ years; or BS with 10+ years
- Strong background in process development, scale-up, or manufacturing of nanoparticle or LNP-based systems
- Experience working with nucleic acid formulations (e.g., mRNA, DNA)
- Familiarity with T mixing (or similar) and characterization techniques such as DLS and encapsulation assays
- Demonstrated ability to design experiments, analyze data, and solve complex technical problems
- Strong communication and collaboration skills
Benefits
- Opportunity to work at the forefront of LNP formulation innovation
- Collaborative, science-driven culture with high impact research
- Competitive compensation and benefits package including healthcare coverage, annual incentive program, and retirement benefits
About the Company
Serif Biomedicines is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases. Founded by Flagship Pioneering, Serif is part of an ecosystem of innovation dedicated to solving major needs in human health through proprietary biological and engineering approaches.
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Serif Biomedicines · Cambridge
