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Posted 5 hours ago
Scientist, Cell Biology & Antibody Engineering
MedraScientist, Cell Biology & Antibody Engineering
Perks & benefits
Relocation AllowanceMedical InsuranceHealth InsurancePaid LeaveCommission
Requirements
Ph.D. with 2+ years industry experience or B.S./M.S. with 6+ years, Mammalian cell culture expertise, Flow cytometry expertise, Antibody characterization experience, Strong documentation skills
Skills
Cell BiologyAntibody EngineeringFlow Cytometry
About the role
About the Company
At Medra, our mission is to use AI, robotics, and biology to accelerate life science research, with the ultimate goal of eradicating disease. We are building a Physical AI Scientist platform that combines autonomous scientific reasoning with robotic dexterity.
Responsibilities
- Design, execute, and interpret antibody screening and characterization campaigns
- Develop and run cell-based binding and functional assays using flow cytometry
- Perform biophysical characterization including SPR, BLI, and epitope binning
- Execute developability assays such as thermal stability, aggregation, and expression titer
- Maintain and engineer mammalian cell lines (Expi293, ExpiCHO, HEK293, CHO)
- Build new lab capabilities including instrument qualification and SOP writing
- Partner with roboticists and software engineers to translate manual workflows into autonomous protocols
- Maintain rigorous experimental records in electronic lab notebooks (ELN)
Requirements
- Ph.D. in cell biology, immunology, biochemistry, or related field with 2+ years of industry experience, or B.S./M.S. with 6+ years of industry experience
- Strong background in mammalian cell culture and sterile technique
- Deep hands-on expertise in flow cytometry and panel design
- Experience designing cell-based functional assays for antibody characterization
- Working understanding of antibody structure, function, and therapeutic discovery
- Ability to drive multiple workstreams in parallel with strong documentation habits
Preferred Qualifications
- Experience screening antibodies against challenging targets like GPCRs or ion channels
- Experience with VHHs, bispecifics, Fc-fusions, or ADCs
- Hands-on experience with lab automation and liquid handling platforms
- Experience expressing and purifying antibodies in HEK293/CHO systems
- Track record of developing new assays or platforms from scratch
Benefits
- Significant equity ownership
- 401k
- Medical and dental insurance
- Unlimited PTO
- Weekday lunches and dinners
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Medra · San Francisco
