Scientist

Responsibilities

• Run cellular assays using cell lines and human primary cells to assess antibody efficacy, potency, and mechanism of action (MOA)
• Perform critical laboratory experiments and data analysis to support strategic decision-making within project teams
• Engage with scientific literature to understand target biology and identify new assay methods
• Develop expertise in imaging-based assays and refine internal laboratory capabilities
• Manage day-to-day laboratory operations, including maintaining a safe environment and ordering consumables
• Mentor junior scientists in novel cell biology techniques and methodologies
• Gather, analyze, and present data to the wider team and organization
• Maintain accurate and detailed laboratory experimental records

Requirements

• PhD in Immunology or a related field, or equivalent level of laboratory experience
• Proven expertise in human primary cell culture and in vitro/ex vivo assays
• Proficiency in cell biology techniques including flow cytometry, ELISA (plate or bead-based), and fluorescence microscopy
• Strong organizational and interpersonal skills with the ability to work both independently and collaboratively
• Excellent written and oral communication skills
• Ability to work efficiently with strong attention to detail in a fast-paced environment

Preferred Qualifications

• Experience in human primary cell antibody screening assay development (high and medium throughput)
• Experience with complex in vitro models such as organ-on-a-chip or organoids
• Experience working with myeloid cells and performing differentiation assays
• Proficiency in fluorescent imaging analysis and quantification software (e.g., Molecular Devices InCarta)
• Experience with omics-based approaches such as RNA-seq

About the Company

AbbVie is a global research-driven biopharmaceutical company dedicated to discovering and delivering innovative medicines that solve serious health issues. At DJS-AbbVie in Oxford, we combine the agility of a specialist discovery team with the scale and resources of a global leader to advance new therapeutics through cutting-edge immunological research.