Process Dev Engineering Senior Scientist, Media Development

Responsibilities

• Develop robust and cost-effective cell culture media for commercial scale manufacturing
• Define and implement technical roadmaps for media development and optimization
• Troubleshoot complex raw material sourcing and control challenges within GMP and regulatory requirements
• Develop and optimize high-throughput, small-scale media screening toolboxes
• Stay current with emerging analytical tools and omics technologies to drive hypothesis-guided optimization
• Generate and review technical reports, regulatory filings, patents, and external publications
• Support media preparation protocol transfer to pilot teams and assist with GMP manufacturing tech transfer
• Lead by example through hands-on laboratory experiments and potential mentoring of junior employees

Requirements

• PhD with 2-5 years of relevant industry experience, MS with 6-9 years, or BS with 8-11 years
• Strong fundamental knowledge in cell culture metabolism and biological pathways
• Extensive experience in media development (stem cell culture experience preferred)
• In-depth understanding of cell culture process development, perfusion processes, and bioreactors across scales
• Proficiency with statistical principles and Design of Experiments (DOE)
• Working knowledge of cGMP environments
• Excellent verbal and written communication skills
• Ability to work on-site in Boston, MA, and participate in weekend work rotations

About the Company

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company is recognized for its work in treating the underlying causes of multiple chronic, life-shortening genetic diseases and continues to advance a robust clinical pipeline across various modalities.