Principal, Quantitative Scientist

About the Company

Pedestal Health (formerly Target RWE) combines deep health system partnerships, longitudinal data curation at scale, and modern study design to build continuous, high-quality evidence for life sciences organizations. The company partners with pharmaceutical and biotech companies, providers and payers to generate rigorous, multimodal evidence that supports clinical, regulatory and strategic decision-making across the full lifecycle of care.

Responsibilities

• Guide the design of observational studies using real-world data, including retrospective and prospective analyses
• Apply statistical and epidemiologic methods in a practical, fit-for-purpose way
• Develop and review study protocols and statistical analysis plans
• Ensure analyses are reproducible, interpretable, and aligned with regulatory and scientific expectations
• Lead client meetings to explain study design, methodology, and results
• Translate complex analytical concepts into clear, accessible language for diverse audiences
• Support business development efforts by communicating scientific approach and data value
• Partner with Product, Engineering, Medical Science, Clinical Operations, and Commercial teams
• Mentor team members on balancing methodological rigor with practical execution

Requirements

• PhD or MS in biostatistics, epidemiology, health economics, data science, or a related field
• 10+ years of experience working with real-world data (EMR, claims, registry, or clinical trial data)
• Strong foundation in observational study design and applied statistical methods
• Working knowledge of R and/or SQL
• Experience working directly with clients or external partners in life sciences or healthcare
• Excellent communication and presentation skills

Benefits

• Comprehensive health, dental, and vision for you and your family
• 401(k) with company match
• Generous PTO and company holidays
• Paid parental leave