Principal Hardware Engineer at Astera Neuro - ScoutJobs - The AI-curated global job board
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Posted 11 hours ago

Principal Hardware Engineer

Astera NeuroPrincipal Hardware Engineer, Precision Instrumentation

Requirements

Precision hardware design experience, Mechanical design and fabrication fundamentals, Prototyping (CNC, 3D printing), End-to-end instrument ownership, Mentorship and leadership experience

Skills

Mechanical DesignRoboticsCAD

About the role

About the Company

Astera Neuro is a neuroscience research company deciphering how activity across billions of neurons becomes thoughts, perceptions, and the conscious experience of the world and ourselves. We develop cutting-edge hardware, recording systems, and software, with the goal of enabling the next generation of discoveries about neural circuits, cognition, and behavior.

Responsibilities

  • Design and build precision mechanical systems, such as titanium microfixtures and micrometer-precision electrode drives
  • Develop components for custom microscopes and optical systems, including alignment and mounting hardware
  • Create custom laboratory instrumentation and surgical or experimental robotics
  • Design electronics and control hardware to interface mechanical systems with data acquisition
  • Equip and run the design and prototyping facility, including tooling and workflows
  • Drive technical direction, mentor engineers, and set engineering culture and standards

Requirements

  • Proven track record of building precision hardware in high-precision industries (medical devices, robotics, aerospace, or semiconductor)
  • Deep fundamentals in mechanical design and fabrication
  • Ability to work from rough ideas and iterate through prototyping (machining, 3D printing, outsourcing)
  • Experience owning complex instruments end-to-end from concept to reliable operation
  • Experience equipping and running a workshop, makerspace, or prototyping facility
  • Experience mentoring engineers or setting engineering standards
  • Background in mechanical, electrical, or biomedical engineering, physics, or related fields

Preferred Qualifications

  • Experience with small precise parts, tight tolerances, and precision motion
  • Hands-on electronics design including PCB layout and embedded systems
  • CAD/CAM proficiency with hands-on machining (CNC, lathe, mill)
  • Experience integrating hardware with data acquisition systems (DAQ, TTL, SPI)
  • Familiarity with electrophysiology or low-volume, high-complexity hardware environments
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Principal Hardware Engineer

Astera Neuro · Emeryville

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