Principal Biostatistician

Responsibilities

• Work directly in clinical trial datasets to identify efficacy signals, safety patterns, and subgroup effects that inform pipeline and commercialization decisions
• Build rigorous statistical analyses including mixed-effects models, longitudinal models, Bayesian frameworks, and sensitivity analyses across pipeline assets
• Monitor emerging safety signals in real time and contextualize findings for leadership
• Pressure-test clinical assumptions, challenge endpoint choices, and scrutinize statistical analysis plans
• Analyze competitor trial data and synthesize evidence from literature, registries, claims, and proprietary datasets into coherent narratives
• Drive selection and integration of data sources and help build shared analytical infrastructure across the platform

Requirements

• Advanced degree in biostatistics, statistics, epidemiology, or a closely related quantitative field; direct experience in clinical trial statistics strongly preferred
• Hands-on fluency with patient-level clinical trial datasets
• Deep command of statistical methods: mixed-effects models, longitudinal and repeated-measures analyses, Bayesian approaches, multiplicity adjustment, and sensitivity analyses
• Familiarity with clinical trial design and regulatory statistical frameworks (ICH E9, estimands, SAP development)
• Track record of translating rigorous analysis into decisions
• Ability to present complex statistical findings clearly to non-technical and CEO-level audiences

Benefits

• Meaningful equity participation
• Comprehensive company-sponsored benefits package
• Base salary generally between $130,000 and $220,000 per year

About the Company

Roivant Sciences seeks to improve health by rapidly delivering innovative medicines and technologies to patients through a unique, decentralized model of focused companies ("Vants"). Since 2014, five new medicines have been approved off the Roivant platform, and the company has built multiple public biotechs spanning computational drug discovery, healthcare data exchange, and novel therapeutic platforms. Roivant embraces diversity and strives to ensure every employee is supported in reaching their full potential.