Postdoctoral Fellow, Functional Genomics

Responsibilities

• Design, optimize, scale, and carry out large-scale Perturb-seq experiments in iPSC-derived immune cells and immortalized cell lines
• Design, optimize, and validate CRISPR functional genomics technologies to obtain higher quality, more complex data about cell-state regulation in human cells
• Culture and differentiate iPSCs into immune cell types such as T-cells and macrophages
• Partner with AI researchers to process and interpret large-scale single-cell datasets
• Collaborate across disciplines to understand systems-level reprogramming of human immune cells

Requirements

• PhD in molecular biology, systems biology, genetics, biomedical engineering, or related field
• Proven expertise in large-scale functional genomics assays and method development
• Experience designing and executing pooled CRISPR screens and/or compound perturbation assays
• Ability to independently design rigorous experiments and troubleshoot complex workflows

Preferred Qualifications

• Experience with CRISPR screening in iPSCs and primary immune cells
• Experience analyzing large-scale genomics datasets
• Working knowledge of R or Python and single-cell analysis tools
• Experience with cytokine or small molecule immune cell assays

Benefits

• Generous employer match on 401(k) contributions
• Paid time off to volunteer
• Funding for select family-forming benefits
• Relocation support

About the Company

Biohub is a large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof to accelerate scientific discovery and cure disease.