
Posted 23 days ago
Pharmacology Research Scientist
VertexPharmacology Research Scientist
Requirements
Ph.D. in biology or pharmacology, Expertise with genetically modified mouse models, In vivo techniques (CRISPR, RNAi, viral transgene expression), Small animal handling, dosing and surgery, Molecular biology (qPCR, western blotting, IHC, ELISA), Knowledge of in vivo regulatory frameworks
Skills
CRISPR
About the role
Responsibilities
- Design and execute technically challenging experiments using disease-relevant genetically modified mouse models
- Identify optimal methodologies including in vivo, ex vivo, and molecular biology/biochemistry to develop novel readouts
- Analyse complex datasets and communicate results clearly within the context of in vivo project strategy
- Collaborate with the In Vivo Pharmacology team and other cross-functional groups to enable project delivery
- Maintain accurate scientific records in compliance with internal and Home Office standards
Requirements
- Ph.D. in biology, pharmacology, or a relevant field with wet lab experience
- Expertise with genetically modified mouse models and in vivo techniques such as CRISPR, RNAi, or viral transgene expression
- Practical skills in small animal handling, dosing, and surgery
- Proficiency in molecular biology and biochemistry techniques including qPCR, western blotting, IHC, and ELISA
- Strong problem-solving skills and a proven ability to deliver high-quality results
- Familiarity with the regulatory frameworks surrounding in vivo research
- Excellent communication and teamwork skills
About the Company
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company is dedicated to treating the underlying causes of multiple chronic, life-shortening genetic diseases and continues to advance a robust clinical pipeline across various therapeutic modalities.
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Vertex · Oxford
