Ph.D. Student Researcher Stipend

Responsibilities

• Identify potential pathogenic variants that cause epilepsy.
• Develop molecular modeling of wild type and mutant forms of ion channels using bioinformatics tools like Homology Modeling.
• Validate models for functions such as ion conductance or ion influx through Molecular Dynamics Simulation.
• Perform high-throughput in silico virtual screening of drug molecules from drug bank databases using Molecular Docking Studies on the BIOVIA platform.
• Evaluate lead targets by running Molecular Dynamics Simulations to test their effect on ion channel function.
• Support the experimental validation of potential repurposed drugs for epilepsy treatment.

Requirements

• Current enrollment in a Ph.D. program.
• Strong understanding of pharmacogenetics literature.
• Technical expertise in Molecular Dynamics simulation, specifically using Discovery Studio.
• Demonstrated working knowledge and preliminary simulation results supporting the project goals.
• Ability to conduct independent research and collaborate with research advisors and CoE Research Scientists.

About the Company

Long Island University (LIU) hosts a leading Dassault Systèmes Center of Excellence (CoE) in Life Sciences. Through our collaboration with Dassault Systèmes, we are spearheading the digital transformation of life science, education, and clinical practice by leveraging advanced computational methods, AI, and in-silico modeling to develop "Virtual Twins" for precision medicine.