ML Engineer, Biological Analysis & Simulation

About the Company

Mithrl is building the world’s first commercially available AI Co-Scientist. It is a discovery engine that transforms messy biological data into insights in minutes, helping scientists generate novel targets, hypotheses, and patent-ready reports.

Responsibilities

• Build AI driven analysis agents that perform biological reasoning across a wide range of datasets
• Develop the standard analysis suite for each dataset, including modules for differential expression, pathway analysis, and clustering
• Build multi step workflows that combine ML models, statistical logic, and biological knowledge
• Design and implement agentic reasoning strategies to synthesize outputs into scientific narratives
• Integrate simulation and modeling tools for small molecule drug discovery, such as ADMET prediction and docking scoring
• Collaborate with data engineering and bioinformatics teams to ensure data consistency
• Validate results and ensure scientific accuracy and reproducibility

Requirements

• Strong experience in machine learning, computational biology, or scientific ML
• Experience developing analysis modules for biological or scientific datasets
• Familiarity with target discovery, gene expression analysis, or statistical modeling
• Hands-on experience with computational chemistry or simulation tools (ADMET, docking, molecular generative models)
• Proficiency in Python and scientific computing libraries
• Experience designing multi step reasoning or workflow based ML pipelines
• Ability to translate scientific questions into structured analytical workflows

Preferred Qualifications

• Experience with LLM powered scientific agents or multi agent architectures
• Familiarity with phenotype based discovery or systems biology
• Background in computational chemistry or structure based drug discovery
• Experience with biological ontologies or curated knowledge graphs
• Prior experience in a tech bio company or biotech R&D group

Benefits

• Comprehensive PPO health coverage through Anthem (medical, dental, and vision)
• 401(k) with top-tier plans