Medical Director, Clinical Development, Oncology

About the Company

Pathos is building a next-generation biotech with AI at the core. We are building the largest foundation model in oncology and pairing it with proprietary AI systems and deep oncology expertise to make drug development decisions with more precision, much earlier.

Responsibilities

• Lead medical review of trial data, including ongoing eligibility, protocol deviations, and safety signals
• Assess key safety-related serious adverse events and direct site education on safety management
• Draft clinical protocols, owning study design, target patient population, and safety risk mitigation
• Translate Oncology Foundation Model predictions and real-world evidence into clinical strategies
• Author clinical content for CSRs, regulatory reports, briefing books, and submission documents
• Identify and build relationships with principal investigators and KOLs
• Provide oversight and medical accountability across active studies

Requirements

• MD required, or US equivalent
• 2+ years of biotech or pharma industry experience in oncology clinical trial development (Phase I, II, and III)
• Experience designing biomarker driven trials
• Ability to travel up to 30%, domestic and international
• Demonstrated ability to lead teams cross-functionally
• Comfort interpreting AI-generated predictions and scenario analyses

Preferred Qualifications

• Specialty training in Medical Oncology
• Direct experience with patient selection strategies grounded in molecular or computational evidence
• Experience using AI tools or agentic workflows to accelerate medical monitoring or regulatory authoring
• Prior leadership of cross functional asset teams from candidate selection through clinical readout