Manager, Statistical Genetics

Responsibilities

• Conduct genetic association analyses using large-scale human genetic data, including GWAS, EXWAS, rare variant analysis, and Mendelian randomization.
• Integrate genetic data with multi-omic datasets to support therapeutic target discovery and validation.
• Develop and implement methods for data harmonization and normalization across in-house and public data resources.
• Apply functional genomic data to prioritize variants and genes of interest.
• Perform quality control on large-scale genetic and phenotypic datasets.
• Design and independently execute analytic studies from conception to completion.
• Collaborate with pre-clinical and clinical development teams to advance therapeutic programs.

Requirements

• PhD with at least 3+ years of relevant experience.
• Expertise in genetic association analyses using large-scale genetic data.
• Proficiency in multi-omic data integration for therapeutic target discovery.
• Strong programming skills in Python, R, C/C++, Bash, or Julia.
• Strong quantitative skills in regression, classification, Bayesian inference, and hypothesis testing.
• Ability to lead research projects and communicate results to diverse technical audiences.

Preferred Qualifications

• Experience working with immunologic datasets and/or experience with immunology.
• Experience with analytic and visualization tools including Git/Github, Claude, Adobe, or Docker.

Benefits

• Health and wellness programs including medical, dental, vision, life, and disability insurance.
• 401(k) company match and equity awards.
• Annual bonuses and paid time off.
• Family support benefits and paid leaves (e.g., military and parental leave).

About the Company

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led by physician-scientists, the company focuses on translating science into medicine to treat eye diseases, cancer, cardiovascular diseases, and more.