Histotechnologist

About the Company

At Nudge, our mission is to develop the best technology for interfacing with the brain to improve people's lives. We're developing a non-invasive, ultrasound-based device that can stimulate and image the brain at high resolution and depth.

Responsibilities

• Perform routine and advanced histological processing of rodent brain tissue, including perfusion, prosection, fixation, embedding, and sectioning
• Execute standard histological stains (H&E, special stains) and immunohistochemistry using manual and automated platforms
• Operate and optimize tissue clearing platforms for whole-brain and thick-section imaging
• Prepare cleared tissue for light sheet fluorescence microscopy and volumetric 3D imaging
• Operate and maintain automated sectioning and tissue processing systems
• Prepare and process samples for spatial omics platforms, including multiplexed protein imaging and spatial transcriptomics
• Develop, optimize, and document SOPs for histological workflows
• Collaborate with research scientists to adapt tissue processing and staining strategies

Requirements

• At least 3 years of industry experience in histotechnology
• Hands-on experience processing rodent brain tissue
• Proficiency in microtomy (paraffin, cryo, vibratome), tissue embedding, H&E staining, and immunohistochemistry
• Experience with at least one tissue clearing method and light sheet microscopy
• Familiarity with automated staining and sectioning platforms
• HT(ASCP) certification or equivalent training
• Bachelor’s degree in biology, neuroscience, or a related field preferred