Associate Scientist/Scientist I, LNP Formulations

Responsibilities

• Design, formulate, and characterize lipid nanoparticle (LNP) systems for nucleic acid delivery across early research and preclinical development stages
• Develop and optimize formulation processes, including microfluidic mixing and scale-up approaches such as TFF and ultrafiltration
• Screen and evaluate novel ionizable lipids and LNP compositions to analyze structure–function relationships
• Troubleshoot formulation and process challenges to enhance robustness, reproducibility, and scalability
• Generate high-quality, reproducible data and maintain thorough documentation in electronic lab notebooks
• Collaborate cross-functionally with analytical, translational, and technology development teams to advance platform goals
• Present data and insights clearly to internal teams to contribute to scientific decision-making

Requirements

• Ph.D. with 0-1 years of experience, M.Sc. with 4+ years of experience, or B.Sc. with 6+ years of experience in a relevant field (Pharmaceutical Sciences, Biomedical Engineering, Biochemistry, etc.)
• Hands-on experience in nanoparticle or LNP formulation and characterization
• Strong understanding of drug delivery systems, particularly for nucleic acid therapeutics
• Proficiency with nanoparticle characterization techniques including DLS and zeta potential
• Demonstrated ability to design, execute, and troubleshoot experiments independently
• Strong data analysis, documentation, and communication skills

Preferred Qualifications

• Familiarity with formulation process technologies such as microfluidic mixers, pumping systems, and TFF
• Experience with high-throughput formulation screening approaches
• Knowledge of lipid chemistry, ionizable lipid design, or bioconjugation techniques
• Experience supporting in vivo studies or translating formulations from research to preclinical scale

Benefits

• Healthcare coverage
• Annual incentive program
• Retirement benefits

About the Company

Mirai Bio is a privately-held, Flagship-founded biotechnology company delivering genetic medicines from promise to performance. We solve the central challenge of achieving precise, scalable delivery of diverse nucleic acid payloads to specific cells and tissues. By combining proprietary in vivo biodistribution datasets, machine learning-guided LNP optimization, and integrated manufacturing capabilities, Mirai helps partners accelerate development and pursue high-value programs.