Associate Scientist I, Nanoparticle Process Development

About the Company

Strand Therapeutics is a clinical-stage biotechnology company pioneering programmable mRNA therapeutics to unlock the full potential of genetic medicines. Founded by MIT synthetic biology pioneers, Strand is advancing a pipeline focused on oncology and autoimmune diseases using its proprietary Signal Stack platform.

Responsibilities

• Execute experiments related to LNP mixing and downstream purification/filtration to improve the process
• Contribute to development of a robust formulation process with emphasis on scale-up, tech-transfer and stability
• Contribute to thorough characterization of LNPs by existing methods and collaborate with internal stakeholders on developing new methods
• Coordinate with other team members to support the group's research activities in a fast-paced and collaborative environment

Requirements

• B.S. or Advanced Degree with 1-2 years of relevant experience
• Experience with LNPs required
• Experience with TFF required
• Strong collaboration and interpersonal skills
• Ability to multi-task and prioritize to meet deadlines

Preferred Qualifications

• Educational focus in Chemical Engineering, Bioengineering or similar
• Experience with nucleic acid payloads
• Experience with TFF with emphasis on LNPs
• Experience with QbD principles, scale up efforts and JMP DOE
• Experience with various mixing geometries or large scale LNP production