Associate Director, Pharmacology

About the Company

Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines for patients with serious diseases by unlocking biologically important targets long considered undruggable. The company has pioneered a new class of alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that have historically been beyond the reach of conventional medicines.

Responsibilities

• Lead nonclinical pharmacology strategy for assigned oncology programs from late discovery through IND submission
• Design, oversee, interpret, and communicate in vivo PK/PD and efficacy studies via internal teams and CRO partnerships
• Contribute to IND-enabling study design and author or co-author relevant pharmacology sections of regulatory submissions
• Integrate pharmacology data with DMPK, safety, and biomarker findings to inform development decisions
• Present data and strategy updates to senior leadership and governance teams
• Inspire and mentor junior pharmacology team members

Requirements

• PhD in Pharmacology, Biology, or related field
• 8+ years post-degree experience
• Minimum of 2+ years of program leadership and people management experience
• Experience supporting first-in-class or novel mechanism oncology programs
• Experience with small molecules, peptides, degraders (e.g., PROTACs), or biologics
• Demonstrated success advancing at least one oncology program to development candidate nomination
• Experience contributing to an IND submission
• Strong expertise in in vivo pharmacology, PK/PD modeling concepts, and mechanistic biomarker strategy
• Proficiency in utilizing AI tools for day-to-day work
• Ability to work on-site and attend in-person meetings

Preferred Qualifications

• Advanced or innovated use of AI tools