Associate Director, Clinical Operations

About the Company

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins.

Responsibilities

• Oversee CRO oversight, execution, and management of clinical trials
• Adhere to Clinical SOPs, GCP, and ICH Guidelines
• Manage study delivery goals, timelines, and designated program budgets
• Guide assessment, selection, engagement, and management of appropriate vendors
• Lead risk management and quality efforts to ensure study compliance and inspection readiness
• Provide proactive oversight of CRO and vendor performance
• Contribute to the strategy and execution of the Clinical Development Plan (CDP)
• Lead line management responsibilities including hiring, performance management, and mentorship
• Collaborate with cross-functional teams including Clinical Development, Regulatory, QA, Finance, and Legal

Requirements

• RN or Bachelor’s or Master’s degree in biological sciences or health-related field
• 11+ years of direct Clinical Operations experience in pharmaceutical or biotech industry
• Minimum of 5 years of project and first-line management experience
• Experience in oncology
• Experience leading and managing global phase 1-3 clinical trials
• Strong working knowledge of FDA Regulations, ICH Guidelines, and GCP
• Experience with vendor management and CRO oversight
• Proficiency in Microsoft Office Suite
• Ability to travel approximately 25%

Preferred Qualifications

• Success working with vendor systems/portals (e.g., eTMF, EDC, IRT, CTMS)
• Early and/or late stage oncology experience
• Knowledge of Ex-US region(s) clinical trial operations
• Experience with cooperative group studies and investigator sponsored trials