Antibody Engineer

About the Company

Chai is a research lab working on generative models for molecular design. We are building AI infrastructure to engineer new medicines with speed and precision. Our mission is to unlock progress towards better cures and better science.

Responsibilities

• Evaluate, expand, and apply the capabilities of de novo antibody design models
• Probe the design space for novel targets and formats
• Validate in silico solutions for function in the lab
• Distill empirical rules from experimental results
• Execute experimental programs at scale to guide, train, and evaluate next-generation models
• Partner with AI research teams and scientists from leading pharmaceutical companies

Requirements

• PhD or equivalent experience in Antibody Engineering, Computational Biology, or Protein Sciences
• Hands-on experience with design and characterization of antibody-based biologics
• Proficiency in molecular-biology workflows
• Experience with binding and developability assays
• Ability to inspect structures in PyMOL or similar tools
• Strong track record of communication, collaboration, and execution

Preferred Qualifications

• Experience in computational protein design
• Ability to work at the intersection of applied biology and artificial intelligence